Four police officers have been stabbed after being called to a disturbance in north-west London.
Witnesses said a man had been chased by police in and out of shops before he fled into a butchers, grabbed a knife and attacked the officers.
Two of the PCs were seriously hurt and one suffered a broken hand during Saturday's incident in Kingsbury Road.
A 32-year-old man was arrested on suspicion of attempted murder.
Ch Supt Dalwardin Babu, the borough commander for Harrow, said one of the officers was stabbed in the stomach, a second suffered head injuries and a stab to the arm, the third officer received a stab wound to the leg and the fourth officer, who was slashed, suffered a broken hand.
Knife grabbedMetropolitan Police Commissioner Bernard Hogan-Howe said he was concerned for the four PCs, all of whom were taken to hospital. He added that two of them were in a serious condition.
Describing the incident, shopkeeper Girish Modha said: "A man was shouting at police in a small alleyway next to a hairdresser's shop which neighbours mine.
"He grabbed a piece of fluorescent tubing and brandished it at police.
"He then ran down Kingsbury Road, going into a cash-and-carry shop. At one point I think he threw a brick and smashed a police car window.
"He then ran round the roundabout and carried on towards the Tube station.
"He went into a butcher's, got a knife and that's when the stabbing took place."
The hairdresser's shop, Mr Modha's sweet shop and a chemist were cordoned off.
The officers are believed to have been attacked at the Kingsbury Halal Butchers, which is located on a busy shopping street opposite Kingsbury Tube station.
Ketan Vyas, the manager of a cash-and-carry store, VB and Sons, said a man aged in his 30s or 40s had burst into the shop chased by police.
Mr Vyas said: "He picked up some cans of beans and threw them at the police and then carried on running out of the store and down the road.
"There were a lot of police after him. He was only in here for a few seconds."
Describing the aftermath of the incident a worker at a Carphone Warehouse shop opposite Kingsbury Halal Butchers said: "I saw about eight police officers on top of a man.
"Ambulances arrived to take away the injured policemen and the man was also taken away."
'Conscious and breathing'A spokeswoman for London Ambulance Service said they took five patients to hospital after being called to the scene at 08:50 GMT.
She said: "We sent two single responders in cars, four ambulance crews and a duty officer.
"We treated five patients, they were all conscious and breathing, and they were taken to hospital."
Barry Gardiner, MP for Brent North, who came to the area following the incident, said he was "deeply upset" and the mood in the area was "very sombre".
Four of the injured people were officers, but the identity of the fifth person who was taken to hospital is yet unknown.
The incident took place near Kingsbury Circle, where Kingsbury Road and Kenton Road meets.
Kingsbury Circle has been closed in all directions following the incident and five bus routes have been diverted.
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